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Search for "cellular toxicity" in Full Text gives 15 result(s) in Beilstein Journal of Nanotechnology.
Nanocarrier systems loaded with IR780, iron oxide nanoparticles and chlorambucil for cancer theragnostics
Beilstein J. Nanotechnol. 2024, 15, 180–189, doi:10.3762/bjnano.15.17
- approximately 60%. At 72 h, the viability was lower than that at 48 hours. The cellular toxicity at concentrations of 1 mg/mL and 1.5 mg/mL at 48 and 72 h was the same. At 72 h, the concentration of F127@NP and F127-folate@NP was significantly lower than that of PVA-NP. No significant differences existed
Antibody-conjugated nanoparticles for target-specific drug delivery of chemotherapeutics
Beilstein J. Nanotechnol. 2023, 14, 912–926, doi:10.3762/bjnano.14.75
- structures; therefore, antibodies are extensively used for protein recognition and targeting [19]. The mAbs are highly specific and capable to induce selective cellular toxicity by binding with specific target antigens, which results in cell lysis either by antibody-dependent cellular cytotoxicity
Recent advances in green carbon dots (2015–2022): synthesis, metal ion sensing, and biological applications
Beilstein J. Nanotechnol. 2022, 13, 1068–1107, doi:10.3762/bjnano.13.93
- as a dual sensor for tetracycline and ʟ-lysine. The fluorescence of CDs is quenched by adding tetracycline and regained by introducing ʟ-lysine [18]. Palmyra leaves were utilized by Athinarayanan et al. for the production of CDs. The cellular toxicity of the CDs was analyzed, and the CDs were found
Ethosomal (−)-epigallocatechin-3-gallate as a novel approach to enhance antioxidant, anti-collagenase and anti-elastase effects
Beilstein J. Nanotechnol. 2022, 13, 491–502, doi:10.3762/bjnano.13.41
- formulation, and different concentrations of EGCG. These results are given in Figure 1. These obtained high viability rates demonstrate that all EGCG concentrations of 500 µg/mL and below, which is the initial concentration in the preparation of ETHs, did not cause any cellular toxicity. In addition, the
Photothermal ablation of murine melanomas by Fe3O4 nanoparticle clusters
Beilstein J. Nanotechnol. 2022, 13, 255–264, doi:10.3762/bjnano.13.20
- during NIR irradiation NPCs caused overt apoptosis and necrosis in a dosage-dependent manner (Figure 3a). The strongest effect was observed for the sample with 0.25 mg/mL NPCs. NPCs alone, on the contrary, did not affect cell viability at low concentrations and only caused signs of mild cellular toxicity
Comprehensive review on ultrasound-responsive theranostic nanomaterials: mechanisms, structures and medical applications
Beilstein J. Nanotechnol. 2021, 12, 808–862, doi:10.3762/bjnano.12.64
A review on the biological effects of nanomaterials on silkworm (Bombyx mori)
Beilstein J. Nanotechnol. 2021, 12, 190–202, doi:10.3762/bjnano.12.15
- studying cellular toxicity, response to new drugs [78] and environmental pollution. Silkworm (Bombyx mori) is an invertebrate insect widely used as a model organism in life sciences [79] since it has diverse mutant strains, a complete genome sequenced, and a protein database available [80][81]. There are
A review on the green and sustainable synthesis of silver nanoparticles and one-dimensional silver nanostructures
Beilstein J. Nanotechnol. 2021, 12, 102–136, doi:10.3762/bjnano.12.9
- physicochemical characteristics of AgNPs can be tuned in a way to avoid cellular toxicity [71][74][75], which facilitates their biomedical applications. The small size of AgNPs (<100 nm) allows them to accumulate on the extracellular membrane of the bacteria and penetrate inside, which alters the membrane
Interactions at the cell membrane and pathways of internalization of nano-sized materials for nanomedicine
Beilstein J. Nanotechnol. 2020, 11, 338–353, doi:10.3762/bjnano.11.25
- inhibitors, whose action on cells is instead very fast. However, some of these inhibitors lack specificity, they might interfere with multiple pathways, and they can cause cellular toxicity [22][133][158][213]. In contrast to these approaches to block uptake pathways, other strategies can be found in which
Phase inversion-based nanoemulsions of medium chain triglyceride as potential drug delivery system for parenteral applications
Beilstein J. Nanotechnol. 2020, 11, 213–224, doi:10.3762/bjnano.11.16
- Kolliphor HS 15. The experimental results indicate, that nanoemulsions with particles of small and tunable size can be easily formed without homogenization by thermal cycling. Keywords: cellular toxicity; isotonicity; nanoemulsion; phase inversion; solvent free; surface properties; Introduction Nanoscaled
- surfactant show different effects on the final product. For example, these factors influence the feasibility of forming stable nanostructures, they affect the phase inversion zone, the in vitro cellular toxicity and the above mentioned particle and surface properties [3][4][12]. There are marketed drug
- to 146 nm and a high PDI of 0.35 within 8 weeks of storage. Hence, it is strongly recommended to store the nanoemulsions with particles of very small size at chilled conditions. Cellular toxicity of the isotonic nanoemulsions The cellular toxicity of the nanoemulsions NE25, NE50 and NE100 as well as
Toxicity and safety study of silver and gold nanoparticles functionalized with cysteine and glutathione
Beilstein J. Nanotechnol. 2019, 10, 1802–1817, doi:10.3762/bjnano.10.175
- comparison as PVP is one of the most frequently used coating materials for stabilization of AuNPs and AgNPs [73]. Our results on AuNP cellular toxicity corroborate well with a similar study on L929 cells treated with PVP-coated AuNPs [74]. Dissolution experiments revealed that GSH-coated AgNPs at a
Review on nanoparticles and nanostructured materials: history, sources, toxicity and regulations
Beilstein J. Nanotechnol. 2018, 9, 1050–1074, doi:10.3762/bjnano.9.98
- useful in a nanomedicine application as they were found to reduce potential cellular toxicity [152]. However, the major drawbacks of these NPs are that they require more time for synthesis, are difficult to filter, and produce a low yield of NPs, as compared to chemical synthesis [153]. Novel nano
Facile fabrication of luminescent organic dots by thermolysis of citric acid in urea melt, and their use for cell staining and polyelectrolyte microcapsule labelling
Beilstein J. Nanotechnol. 2016, 7, 1905–1917, doi:10.3762/bjnano.7.182
- and cellular toxicity is possible simply by changing the processing parameters, e.g., the ratio of precursors or the duration of synthesis. We have succeeded in the decoration of polyelectrolyte microcapsules with O-dots synthesized in this way, the former being considered very attractive drug
- effect might have been due to the passivation of the particle surface by DMSO molecules [48]. Biological properties of O-dots Cellular toxicity The results of studying the effect of O-dots samples on cell viability and metabolic activity of NADP-H-dependent oxidoreductases are shown in Figure 4 (for more
Silica nanoparticles are less toxic to human lung cells when deposited at the air–liquid interface compared to conventional submerged exposure
Beilstein J. Nanotechnol. 2014, 5, 1590–1602, doi:10.3762/bjnano.5.171
- reasons for the different sensitivity remain unknown. Future studies need to address the relevance of changes in the dose rate as a critical parameter for cellular toxicity. Moreover, more detailed analysis of particle uptake (e.g., by confocal microscopy or TEM) under ALI and submerged conditions will be
The protein corona protects against size- and dose-dependent toxicity of amorphous silica nanoparticles
Beilstein J. Nanotechnol. 2014, 5, 1380–1392, doi:10.3762/bjnano.5.151
- explanation, corona formation reduced ASP30 cellular uptake, which was however not significantly affected by ASP surface charge in our model. Collectively, our study uncovers an impact of ASP size as well as of the protein corona on cellular toxicity, which might be relevant for processes at the nano–bio
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